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NETO2 promotes melanoma progression via activation of the Ca/CaMKII signaling pathway

Frontiers of Medicine 2023, Volume 17, Issue 2, Pages 263-274 doi: 10.1007/s11684-022-0935-0

Abstract: Neuropilin and tolloid-like 2 (NETO2) is closely related to tumorigenesis.invasion by downregulating the levels of calcium ions (Ca2+sup>) and the expression of key genesinvolved in the calcium signaling pathway.Importantly, pharmacological inhibition of CaMKII/CREB activity with the CaMKII inhibitor KN93 suppressedNETO2-induced proliferation and melanoma metastasis.

Keywords： melanoma neuropilin and tolloid-like 2 Ca2+sup>/CaMKII signaling pathway

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Selective recovery of Cu

Haiping LUO,Bangyu QIN,Guangli LIU,Renduo ZHANG,Yabo TANG,Yanping HOU

Frontiers of Environmental Science & Engineering 2015, Volume 9, Issue 3, Pages 522-527 doi: 10.1007/s11783-014-0633-5

Abstract: As the bioelectrochemical system, the microbial fuel cell (MFC) and the microbial electrolysis cell (MEC) were developed to selectively recover Cu and Ni ions from wastewater. The wastewater was treated in the cathode chambers of the system, in which Cu and Ni ions were removed by using the MFC and the MEC, respectively. At an initial Cu concentration of 500 mg·L , removal efficiencies of Cu increased from 97.0%±1.8% to 99.0%±0.3% with the initial Ni concentrations from 250 to 1000 mg·L , and maximum power densities increased from 3.1±0.5 to 5.4±0.6 W·m . The Ni removal mass in the MEC increased from 6.8±0.2 to 20.5±1.5 mg with the increase of Ni concentrations. At an initial Ni concentration of 500 mg·L , Cu removal efficiencies decreased from 99.1%±0.3% to 74.2%±3.8% with the initial Cu concentrations from 250 to 1000 mg·L , and maximum power densities increased from 3.0±0.1 to 6.3±1.2 W·m . Subsequently, the Ni removal efficiencies decreased from 96.9%±3.1% to 73.3%±5.4%. The results clearly demonstrated the feasibility of selective recovery of Cu and Ni from the wastewater using the bioelectrochemical system.

Keywords： bioelectrochemical system Cu2+sup> Ni2+sup> selective recovery

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Apigenin alleviates neomycin-induced oxidative damage via the Nrf2 signaling pathway in cochlear hair

Frontiers of Medicine 2022, Volume 16, Issue 4, Pages 637-650 doi: 10.1007/s11684-021-0864-3

Abstract: Further evidence suggested that the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathwayDisruption of the Nrf2 axis abolished the effects of apigenin on the alleviation of oxidative stress

Keywords： apigenin aminoglycosides ototoxicity oxidative stress Nrf2 signaling pathway

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Study on Algorithm A*sup> Based on Dynamic Representation of Binary Tree for Environment and Robotic

Tang Ping,Yang Yimin

Strategic Study of CAE 2002, Volume 4, Issue 9, Pages 50-53

Abstract: A new algorithm A*sup> , which plans the path of soccer robots in complicated environments is

Keywords： dynamic binary-tree algorithm A*sup> path planning

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Effect of noble metal nanoparticle size on C–N bond cleavage performance in hydrodenitrogenation: a study of active sites

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 12, Pages 1986-2000 doi: 10.1007/s11705-023-2337-5

Abstract: obtained by modulating the reduction temperature, and the catalytic activity was evaluated using 1,2,3,4Results showed a 13 times higher reaction rate for sp3sup>-hybridized C–N bond cleavage than sp2sup>-hybridized C–N bond cleavage, while the reaction rate tended to increase first and then

Keywords： sp3sup>/sp2sup>-hybridized C–N bond noble metal nanoparticle catalytic active site turnover

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Clinical significance of CD34+sup>CD117dimsup>/CD34+sup>CD117brisup> myeloblast-associated

Xueping Li, Yuting Dai, Bing Chen, Jinyan Huang, Saijuan Chen, Lu Jiang

Frontiers of Medicine 2021, Volume 15, Issue 4, Pages 608-620 doi: 10.1007/s11684-021-0836-7

Abstract: t(8;21)(q22;q22) acute myeloid leukemia (AML) is a highly heterogeneous hematological malignancy with a high relapse rate in China. Two leukemic myeloblast populations (CD34 CD117 and CD34 CD117 ) were previously identified in t(8;21) AML, and CD34 CD117 cell proportion was determined as an independent factor for this disease outcome. Here, we examined the impact of CD34 CD117 /CD34 CD117 myeloblast-associated gene expression on t(8;21) AML clinical prognosis. In this study, 85 patients with t(8;21) AML were enrolled. The mRNA expression levels of CD34 CD117 -associated genes ( , , and ) and CD34 CD117 -associated genes ( , , and ) were measured using quantitative reverse transcription PCR. Associations between gene expression and clinical outcomes were determined using Cox regression models. Results showed that patients with high , , or expression had significantly inferior overall survival (OS), whereas those with high or expression showed relatively favorable prognosis. Univariate analysis revealed that CD19, CD34 CD117 proportion, mutation, minimal residual disease (MRD), and expression levels of , , , and were associated with OS. Multivariate analysis indicated that mutation, MRD and and expression levels were independent prognostic variables for OS. Identifying the clinical relevance of CD34 CD117 /CD34 CD117 myeloblast-associated gene expression may provide new clinically prognostic markers for t(8;21) AML.

Keywords： t(8 21)(q22 q22) AML CD34+sup>CD117dimsup>/ CD34+sup>CD117brisup> cell population

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K+sup> and Na+sup> fluxes in roots of two Chinese Iris populations

Pinfang LI,Biao ZHANG

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 2, Pages 144-149 doi: 10.15302/J-FASE-2014016

Abstract: Maintenance of ion homeostasis, particularly the regulation of K and Na uptake, is important for all plants to adapt to salinity. Observations on ionic response to salinity and net fluxes of K , Na in the root exhibited by plants during salt stress have highlighted the need for further investigation. The objectives of this study were to compare salt adaptation of two Chinese Iris ( Pall. var. (Fisch.) Koidz.) populations, and to improve understanding of adaptation to salinity exhibited by plants. Plants used in this study were grown from seeds collected in the Xinjiang Uygur Autonomous Region (Xj) and Beijing Municipality (Bj), China. Hydroponically-grown seedlings of the two populations were supplied with nutrient solutions containing 0.1 (control) and 140 mmol·L NaCl. After 12 days, plants were harvested for determination of relative growth rate and K , Na concentrations. Net fluxes of K , Na from the apex and along the root axis to 10.8 mm were measured using non-invasive micro-test technique. With 140 mmol·L NaCl treatment, shoots for population Xj had larger relative growth rate and higher K concentration than shoots for population Bj. However, the Na concentrations in both shoots and roots were lower for Xj than those for Bj. There was a lower net efflux of K found in population Xj than by Bj in the mature zone (approximately 2.4-10.8 mm from root tip). However, no difference in the efflux of Na between the populations was obtained. Population Xj of continued to grow normally under NaCl stress, and maintained a higher K /Na ratio in the shoots. These traits, which were associated with lower K leakage, help population Xj adapt to saline environments.

Keywords： Koidz population K+sup> and Na+sup> ion flux non-invasive micro-test technique

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Removal of ammonium and nitrate through Anammox and FeS-driven autotrophic denitrification

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 6, doi: 10.1007/s11783-023-1674-4

Abstract:

● Simultaneous NH₄+sup>/NO₃–sup

Keywords： Anammox Denitrification FeS NH₄+sup>/NO₃−sup> Sulfammox

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Ozonation as an efficient pretreatment method to alleviate reverse osmosis membrane fouling caused by complexes of humic acid and calcium ion

Xuehao Zhao, Yinhu Wu, Xue Zhang, Xin Tong, Tong Yu, Yunhong Wang, Nozomu Ikuno, Kazuki Ishii, Hongying Hu

Frontiers of Environmental Science & Engineering 2019, Volume 13, Issue 4, doi: 10.1007/s11783-019-1139-y

Abstract:

Ca2+sup> promoted aggregation of HA molecules

Ozonation eliminated the effect of Ca2+sup> on the RO membrane fouling behavior of HA.

Keywords： Reverse osmosis Membrane fouling Humic acid Ca2+sup> Ozone

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resistance to endocrine therapy in hormone receptor-positive human epidermal growth factor receptor 2-

Wenjie Zhu, Binghe Xu

Frontiers of Medicine 2021, Volume 15, Issue 2, Pages 208-220 doi: 10.1007/s11684-020-0795-4

Abstract: have been developed to overcome resistance to endocrine therapy (ET) and improve the outcome of HR /HER2randomized controlled trials evaluating various targeted therapies in combination with ET in HR /HER2

Keywords： endocrine-resistant HR+sup>/HER2-sup> advanced breast cancer randomized clinical trials

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Calculation of H₂+sup> Structural Parameters based on Hydrogen Atomic Protonized Model

Chen Jing

Strategic Study of CAE 2004, Volume 6, Issue 11, Pages 29-32

Abstract:

The hydrogen atomic protonized model was introduced in present paper for calculation of H₂+sup> structural parameters.above model for bond-length, bond-energy and force constant of hydrogen molecule ion were R_e=2aWhen atomic-unit used,they are respectively R_e= 2au., D_e=0.109735au. and k=0.109735au

Keywords： hydrogen molecule ion bond-length bond-energy force constant

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Performance and mechanism of carbamazepine removal by FeS-SO process: experimental investigation and DFT calculations

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 9, doi: 10.1007/s11783-023-1713-1

Abstract: ListItem>

● Synergistic removal of carbamazepine (CBZ) was obtained in the FeS-S₂O₈2–sup> process.

Keywords： FeS S₂O₈2–sup> Carbamazepine DFT calculations Degradation routes

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Deciphering the effect of sodium dodecylbenzene sulfonate on up-flow anaerobic sludge blanket treatment of synthetic sulfate-containing wastewater

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 5, doi: 10.1007/s11783-020-1385-z

Abstract:

• UASB reactor can work efficiently with high COD/SO₄2sup>-sup> ratios when SDBS exists.

Keywords： Up-flow anaerobic sludge blanket Organic sulfur Sodium dodecylbenzene sulfonate COD/SO₄2sup>−sup> ratio Microbial community

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Advances of 12thsup> CAPS research symposium: young chemists and chemical engineers fronts

Guoping Hu, Baiqian Dai

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 3, Pages 461-463 doi: 10.1007/s11705-020-2026-6

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RNA m6sup>A modification and its function in diseases

Jiyu Tong, Richard A. Flavell, Hua-Bing Li

Frontiers of Medicine 2018, Volume 12, Issue 4, Pages 481-489 doi: 10.1007/s11684-018-0654-8

Abstract:

N6sup>-methyladenosine (m6sup>A) is the most common post-transcriptional RNAsup>A modification could be installed by m6sup>A “writers” composed of core catalyticThe function of m6sup>A is executed by m6sup>A “readers” that bind to m6sup>A directly (YTH domain-containing proteins, eIF3 and IGF2BPs) or indirectly (HNRNPA2B1).However, the mechanism and the regulatory network of m6sup>A are still largely unknown.

Keywords： RNA modification m6sup>A immunity cancer epigenetics

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Title Author Date Type Operation

NETO2 promotes melanoma progression via activation of the Ca/CaMKII signaling pathway

Journal Article

Selective recovery of Cu

Haiping LUO,Bangyu QIN,Guangli LIU,Renduo ZHANG,Yabo TANG,Yanping HOU

Journal Article

Apigenin alleviates neomycin-induced oxidative damage via the Nrf2 signaling pathway in cochlear hair

Journal Article

Study on Algorithm A*sup> Based on Dynamic Representation of Binary Tree for Environment and Robotic

Tang Ping,Yang Yimin

Journal Article

Effect of noble metal nanoparticle size on C–N bond cleavage performance in hydrodenitrogenation: a study of active sites

Journal Article

Clinical significance of CD34+sup>CD117dimsup>/CD34+sup>CD117brisup> myeloblast-associated

Xueping Li, Yuting Dai, Bing Chen, Jinyan Huang, Saijuan Chen, Lu Jiang

Journal Article

K+sup> and Na+sup> fluxes in roots of two Chinese Iris populations

Pinfang LI,Biao ZHANG

Journal Article

Removal of ammonium and nitrate through Anammox and FeS-driven autotrophic denitrification

Journal Article

Ozonation as an efficient pretreatment method to alleviate reverse osmosis membrane fouling caused by complexes of humic acid and calcium ion

Xuehao Zhao, Yinhu Wu, Xue Zhang, Xin Tong, Tong Yu, Yunhong Wang, Nozomu Ikuno, Kazuki Ishii, Hongying Hu

Journal Article

resistance to endocrine therapy in hormone receptor-positive human epidermal growth factor receptor 2-

Wenjie Zhu, Binghe Xu

Journal Article

Calculation of H₂+sup> Structural Parameters based on Hydrogen Atomic Protonized Model

Chen Jing

Journal Article

Performance and mechanism of carbamazepine removal by FeS-SO process: experimental investigation and DFT calculations

Journal Article

Deciphering the effect of sodium dodecylbenzene sulfonate on up-flow anaerobic sludge blanket treatment of synthetic sulfate-containing wastewater

Journal Article

Advances of 12thsup> CAPS research symposium: young chemists and chemical engineers fronts

Guoping Hu, Baiqian Dai

Journal Article

RNA m6sup>A modification and its function in diseases

Jiyu Tong, Richard A. Flavell, Hua-Bing Li

Journal Article

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